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Cynader, Pyruvate Released by Astrocytes Protects Neurons from Copper-Catalyzed Cysteine Neurotoxicity

The interconnectedness of these molecular players underscores the challenge of targeting AD at the molecular level, requiring a multifaceted approach to disrupt these networks effectively

The pKa values of side-chain groups, including side-chain carboxyl and amino groups, depend on the groups chemical nature.The classification of an amino acid as acidic or basic depends on the pKa of the side chain as well as the chemical nature of the group

In contrast, the transcriptomic analysis shows a downregulation of genes associated with glucose metabolism in both cortex and medulla in CKD